Intelligent Systems in Medicine and Health: The Role of AI

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This volume was published in November 2022 by Springer Nature in their Cognitive Informatics (CI) book series, edited by Vimla L. Patel. Conceived as an introductory textbook, the volume is a comprehensive introduction that takes stock of the current state-of-the-art of AI in Medicine (AIM), places these developments in their historical context, and identifies factors that may help or hinder their ability to improve patient care, all from a CI perspective. A reader of this volume will attain an accurate picture of the strengths and limitations of these emerging technologies, emphasizing how they relate to the AI systems that preceded them, to the intelligence of human decision makers in medicine, and to the needs and expectations of those who use the resulting tools and systems. This sets the stage for an informed discussion of the potential of such technology to enhance patient care, the obstacles that must be overcome for this to take place, and the ways in which emerging and as-yet-undeveloped technologies may transform the practice of healthcare. In addition to clinical applications of AI (including translational bioinformatics and precision medicine), the volume covers applications in public health (i.e. at the population level), and ways in which these technologies may influence institutional decision making and education in simulated environments. Informed by this material, the concluding chapters discuss the future of AI in medicine, drawing inference from current trends to identify factors that may impede or accelerate its development and deployment.



Trevor A. Cohen, MBChB, PhD, FACMI, University of Washington,

Vimla L. Patel, PhD, DSc, FRSC, FACMI, New York Academy of Medicine

Edward H. Shortliffe, MD, PhD, MACP, FACMI, Columbia University

Available as both an e-book and in hard copy (671 pages)
Intelligent Systems in Medicine and Health: The Role of AI
T.A. Cohen, V.L. Patel, and E.H. Shortliffe, Editors

Table of Contents

Front Matter (download)


Foreword by Bruce G. Buchanan

Preface and Acknowledgements

Table of Contents and Contributors

I. Introduction

1. Introducing AI in Medicine: A Cognitive Informatics Perspective (download)

Trevor A. Cohen, Vimla L. Patel, and Edward H. Shortliffe

2. AI in Medicine: Some Pertinent History (download)

Edward H. Shortliffe and Nigam H. Shah

3. Data and Computation: A Contemporary Landscape

Ida Sim and Marina Sirota

II. Approaches

4. Knowledge-based Systems in Medicine

Peter Szolovits and Emily Alsentzer

5. Clinical Cognition and AI: From Emulation to Symbiosis

Vimla L. Patel and Trevor A. Cohen

6. Machine Learning Systems

Devika Subramanian and Trevor A. Cohen

7. Natural Language Processing

Hua Xu and Kirk Roberts

8. Explainability in Medical AI

Ron Li, Naveen Muthu, Dev Dash, Tina Hernandez-Boussard, and Nigam Shah

9. Intelligent Agents and Dialog Systems

Timothy Bickmore and Byron Wallace

III. Applications

10. Integration of AI for Clinical Decision Support

Shyam Visweswaran, Andrew J. King, and Gregory F. Cooper

11. Predicting Medical Outcomes

Riccardo Bellazzi, Arianna Dagliati, and Giovanna Nicora

12. Interpreting Medical Images

Zongwei Zhou, Jianming Liang, and Michael Gotway

13. Public Health Applications

David Buckeridge

14. AI in Translational Bioinformatics and Precision Medicine

Thanh Nguyen and Jake Chen

15. Health Systems Management

Adam Wilcox and Beth Britt

16. Intelligent Systems in Learning and Education

Vimla L. Patel and Parvati Dev

IV. The Future of AI in Medicine: Prospects and Challenges

17. Framework for the Evaluation of Clinical AI Systems

Edward H. Shortliffe, Martin-Josè Sepulvèda, and Vimla L. Patel

18. Ethical and Policy Issues

Diane Korngiebel, Anthony Solomonides, and Kenneth Goodman

19. Anticipating the Future of Artificial Intelligence in Medicine and Health Care: A Clinical Data Science Perspective

Anthony Chang

20. Reflections and Projections

Trevor A. Cohen, Vimla L. Patel, and Edward H. Shortliffe

Terms and Definitions (Glossary) (download)

Subject Index